Enrichment analysis of genes downregulated in type 1 diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00060009
TitleEnrichment analysis of genes downregulated in type 1 diabetes mellitus
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by type 1 diabetes mellitus and healthy control cells in the Muscle - Striated (Skeletal) (MMHCC) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bsme
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:346
Cell TypeMuscle - Striated (Skeletal) (MMHCC)
DO IDDOID:9744
Disease Nametype 1 diabetes mellitus
Organismmouse
UMLS CUIC0011854
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM28550, GSM28551, GSM28552, GSM28559, GSM28560, GSM28561
Perturbed SamplesGSM28553, GSM28554, GSM28555, GSM28556, GSM28557, GSM28558
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE1659
Gene Expression Omnibus
Exercise effect on diabetic skeletal muscle: time course
7
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