Enrichment analysis of genes downregulated in chronic myeloid leukemia
Canned Analysis
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General Information
AccessionDCA00060117
TitleEnrichment analysis of genes downregulated in chronic myeloid leukemia
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by chronic myeloid leukemia and healthy control cells in the Haematopoietic stem cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1btz0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:403
Cell TypeHaematopoietic stem cell
DO IDDOID:8552
Disease Namechronic myeloid leukemia
Organismhuman
UMLS CUIC0023473
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM300128, GSM300129, GSM300130, GSM300131, GSM300132, GSM300133, GSM300134, GSM300135, GSM300136, GSM300137, GSM300138, GSM300139, GSM300140, GSM300141, GSM300142, GSM300144, GSM300146, GSM300147, GSM300148, GSM300149
Perturbed SamplesGSM300093, GSM300100, GSM300101, GSM300102, GSM300103, GSM300104, GSM300105, GSM300106, GSM300107, GSM300108, GSM300109, GSM300111, GSM300112, GSM300114, GSM300115, GSM300116, GSM300117, GSM300118, GSM300119, GSM300120, GSM300121, GSM300122, GSM300123, GS
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11889
Gene Expression Omnibus
The hematopoietic stem cell in chronic phase CML is characterized by a transcriptional profile resembling normal myeloid progenitor cells and reflecti...
7
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