Enrichment analysis of genes downregulated in cellular phase chronic idiopathic myelofibrosis
Canned Analysis
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General Information
AccessionDCA00060233
TitleEnrichment analysis of genes downregulated in cellular phase chronic idiopathic myelofibrosis
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by cellular phase chronic idiopathic myelofibrosis and healthy control cells in the hematopoietic CD34+ stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bttv
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatortimkenny92
CREEDS IDdz:460
Cell Typehematopoietic CD34+ stem cells
DO IDDOID:8106
Disease Namecellular phase chronic idiopathic myelofibrosis
Organismhuman
UMLS CUIC1516553
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM76923, GSM76924, GSM76925
Perturbed SamplesGSM76926, GSM76927, GSM76928
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE3410
Gene Expression Omnibus
Idiopathic myelofibrosis: hematopoietic CD34+ stem cells
7
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