Enrichment analysis of genes upregulated in systemic lupus erythematosus
Canned Analysis
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General Information
AccessionDCA00060356
TitleEnrichment analysis of genes upregulated in systemic lupus erythematosus
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by systemic lupus erythematosus and healthy control cells in the synovial biopsies from affected knees cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bsqo
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorvcogliani
CREEDS IDdz:512
Cell Typesynovial biopsies from affected knees
DO IDDOID:9074
Disease Namesystemic lupus erythematosus
Organismhuman
UMLS CUIC0024141
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM898470, GSM899010, GSM899011, GSM899012, GSM899013, GSM899014, GSM899015, GSM899016, GSM899017, GSM899018, GSM899019, GSM899020, GSM899025, GSM899026, GSM899027, GSM899028, GSM899029, GSM899030, GSM899031, GSM899032, GSM899033
Perturbed SamplesGSM899021, GSM899022, GSM899023, GSM899024
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36700
Gene Expression Omnibus
Systemic lupus erythematosus and arthritides: synovial biopsies
7
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