Enrichment analysis of genes downregulated in type 2 diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00060463
TitleEnrichment analysis of genes downregulated in type 2 diabetes mellitus
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by type 2 diabetes mellitus and healthy control cells in the skeletal muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bsvy
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorsaulc07
CREEDS IDdz:581
Cell Typeskeletal muscle
DO IDDOID:9352
Disease Nametype 2 diabetes mellitus
Organismhuman
UMLS CUIC0011860
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM886610, GSM886611, GSM886612, GSM886613, GSM886614, GSM886615, GSM886616, GSM886617, GSM886618, GSM886619
Perturbed SamplesGSM886620, GSM886621, GSM886622, GSM886623, GSM886624, GSM886625
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE36297
Gene Expression Omnibus
Skeletal muscle of patients with inherited insulin resistance
12
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