Enrichment analysis of genes downregulated in APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Canned Analysis
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General Information
AccessionDCA00060501
TitleEnrichment analysis of genes downregulated in APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy and healthy control cells in the Thymic epithelial cell cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bsyd
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:6
Cell TypeThymic epithelial cell
Disease NameAPECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy
Organismmouse
UMLS CUIC0085859
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM2444, GSM2445, GSM2446
Perturbed SamplesGSM2447, GSM2448, GSM2449
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE85
Gene Expression Omnibus
Autoimmune disease mechanisms
12
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