Enrichment analysis of genes upregulated in relapsing-remitting multiple sclerosis
Canned Analysis
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General Information
AccessionDCA00060946
TitleEnrichment analysis of genes upregulated in relapsing-remitting multiple sclerosis
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by relapsing-remitting multiple sclerosis and healthy control cells in the CD4+ T cells Lymphocytes (sorted from PBMCs from monozygotic twin pairs discordant for RRMS) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1btpa
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDdz:879
Cell TypeCD4+ T cells Lymphocytes (sorted from PBMCs from monozygotic twin pairs discordant for RRMS)
DO IDDOID:2378
Disease Namerelapsing-remitting multiple sclerosis
Organismhuman
UMLS CUIC0751967
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM413790, GSM413792, GSM413795, GSM413796
Perturbed SamplesGSM413791, GSM413793, GSM413794, GSM413797
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE16461
Gene Expression Omnibus
Identical twins discordant for Multiple sclerosis: CD4+ and CD8+ T cells
7
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