Enrichment analysis of genes downregulated in type 1 diabetes mellitus
Canned Analysis
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General Information
AccessionDCA00060967
TitleEnrichment analysis of genes downregulated in type 1 diabetes mellitus
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between cells affected by type 1 diabetes mellitus and healthy control cells in the T lymphocyte cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bsy4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorJoel.Dudley
CREEDS IDdz:9
Cell TypeT lymphocyte
DO IDDOID:9744
Disease Nametype 1 diabetes mellitus
Organismhuman
UMLS CUIC0011854
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM266963, GSM266964, GSM266965, GSM266966, GSM266967, GSM266968, GSM266969, GSM266970, GSM266971, GSM266972, GSM266973, GSM266974, GSM266975, GSM266976, GSM266977
Perturbed SamplesGSM266978, GSM266979, GSM266980, GSM266981, GSM266982, GSM266983, GSM266984, GSM266985, GSM266986, GSM266987, GSM266988, GSM266989
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE10586
Gene Expression Omnibus
Expression data from recent-onset T1D patients and controls
7
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