Enrichment analysis of genes downregulated in EP300 KD
Canned Analysis
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General Information
AccessionDCA00063655
TitleEnrichment analysis of genes downregulated in EP300 KD
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between EP300 KD cells and control cells in the CD4+CD25+ Treg cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c16l
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1050
Cell TypeCD4+CD25+ Treg
Gene Symbol (human)EP300
Gene Symbol (mouse)Ep300
Organismmouse
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1164170, GSM1164171, GSM1164172
Perturbed SamplesGSM1164167, GSM1164168, GSM1164169
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47989
Gene Expression Omnibus
Inhibition of p300 impairs Foxp3+ T-regulatory cell function and promotes anti-tumor immunity
7
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