Enrichment analysis of genes upregulated in TFAM KD
Canned Analysis
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General Information
AccessionDCA00063694
TitleEnrichment analysis of genes upregulated in TFAM KD
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between TFAM KD cells and control cells in the murine embryonic fibroblasts (MEFs) cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bwn2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorchrisliu
CREEDS IDgene:1074
Cell Typemurine embryonic fibroblasts (MEFs)
Gene Symbol (human)TFAM
Gene Symbol (mouse)Tfam
Organismmouse
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM1556844, GSM1556845
Perturbed SamplesGSM1556846, GSM1556847
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE63767
Gene Expression Omnibus
Expression analysis of wild-type and Tfam heterozygous knockout (Tfam+/-) murine embryonic fibroblasts (MEFs).
7
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