Enrichment analysis of genes upregulated in IDH2 R140Q Allele
Canned Analysis
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General Information
AccessionDCA00063738
TitleEnrichment analysis of genes upregulated in IDH2 R140Q Allele
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between IDH2 R140Q Allele cells and control cells in the Heart tissue cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c1hi
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1119
Cell TypeHeart tissue
Gene Symbol (human)IDH2
Gene Symbol (mouse)Idh2
Organismmouse
Perturbation TypeR140Q Allele
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM1324881, GSM1324882, GSM1324883, GSM1324884
Perturbed SamplesGSM1324885, GSM1324886, GSM1324887, GSM1324888
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54838
Gene Expression Omnibus
Heart response to isocitrate dehydrogenase 2 mutations IDH2R140Q and IDH2R172K
7
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