Enrichment analysis of genes upregulated in IRAK4 IRAK4 kinase deficient mutant
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00063768
TitleEnrichment analysis of genes upregulated in IRAK4 IRAK4 kinase deficient mutant
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between IRAK4 IRAK4 kinase deficient mutant cells and control cells in the bone-marrow derived macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bwhv
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1131
Cell Typebone-marrow derived macrophages
Gene Symbol (human)IRAK4
Gene Symbol (mouse)Irak4
Organismmouse
Perturbation TypeIRAK4 kinase deficient mutant
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM229589, GSM229590
Perturbed SamplesGSM229595, GSM229596
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE9037
Gene Expression Omnibus
response to LPS of WT and IRAK4 kinase dead mouse bone marrow macrophages
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.