Enrichment analysis of genes downregulated in IFNAR2 KO
Canned Analysis
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General Information
AccessionDCA00063783
TitleEnrichment analysis of genes downregulated in IFNAR2 KO
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between IFNAR2 KO cells and control cells in the bone-marrow derived macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c0r7
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1139
Cell Typebone-marrow derived macrophages
Gene Symbol (human)IFNAR2
Gene Symbol (mouse)Ifnar2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1111106, GSM1111107
Perturbed SamplesGSM1111108, GSM1111109
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE45632
Gene Expression Omnibus
Differential induction of TLR3-dependent innate immune signaling by closely related parasite species_I
7
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