Enrichment analysis of genes downregulated in IRF7 stable IRF7 transfection (pMSCV)
Canned Analysis
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General Information
AccessionDCA00063793
TitleEnrichment analysis of genes downregulated in IRF7 stable IRF7 transfection (pMSCV)
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between IRF7 stable IRF7 transfection (pMSCV) cells and control cells in the 4T1.2 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bzn7
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1146
Cell Type4T1.2
Gene Symbol (human)IRF7
Gene Symbol (mouse)Irf7
Organismhuman
Perturbation Typestable IRF7 transfection (pMSCV)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM928616, GSM928617, GSM928618
Perturbed SamplesGSM928619, GSM928620, GSM928621
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE37828
Gene Expression Omnibus
Silencing of Irf7 pathways in breast cancer cells promotes bone metastasis through immune escape mechanisms
7
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