Enrichment analysis of genes downregulated in E2F4 KO
Canned Analysis
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General Information
AccessionDCA00063839
TitleEnrichment analysis of genes downregulated in E2F4 KO
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between E2F4 KO cells and control cells in the MEF cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bzqx
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorshvetank
CREEDS IDgene:1167
Cell TypeMEF cells
Gene Symbol (human)E2F4
Gene Symbol (mouse)E2f4
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM278989, GSM278990, GSM278991, GSM278992, GSM278993, GSM278994, GSM278995, GSM278996, GSM278997, GSM278998
Perturbed SamplesGSM278999, GSM279000, GSM279001, GSM279002, GSM279003, GSM279004, GSM279005, GSM279006, GSM279007, GSM279008
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE11039
Gene Expression Omnibus
Expression Data from wild type and E2F4 null MEFs
7
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