Enrichment analysis of genes downregulated in MSTN DEPLETION
Canned Analysis
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General Information
AccessionDCA00063921
TitleEnrichment analysis of genes downregulated in MSTN DEPLETION
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MSTN DEPLETION cells and control cells in the mature skeletal muscle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c0rt
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:121
Cell Typemature skeletal muscle
Gene Symbol (human)MSTN
Gene Symbol (mouse)Mstn
Organismmouse
Perturbation TypeDEPLETION
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM385406, GSM385407, GSM385408, GSM385409, GSM385410
Perturbed SamplesGSM385411, GSM385412, GSM385413, GSM385414, GSM385415
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE15349
Gene Expression Omnibus
Myostatin depletion effect on mature skeletal muscle
7
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