Enrichment analysis of genes upregulated in KLF5 KO
Canned Analysis
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General Information
AccessionDCA00064364
TitleEnrichment analysis of genes upregulated in KLF5 KO
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between KLF5 KO cells and control cells in the LSK cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c0q7
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1427
Cell TypeLSK cells
Gene Symbol (human)KLF5
Gene Symbol (mouse)Klf5
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM1071463, GSM1071464, GSM1071465, GSM1071466, GSM1071467, GSM1071468
Perturbed SamplesGSM1071458, GSM1071459, GSM1071460, GSM1071461, GSM1071462
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE43806
Gene Expression Omnibus
Klf5 controls bone marrow homing of stem cells and progenitors through Rab5-mediated membrane Beta1/Beta2-integrin expression
7
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