Enrichment analysis of genes downregulated in ATF6 tamoxifen-induced activation
Canned Analysis
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General Information
AccessionDCA00064445
TitleEnrichment analysis of genes downregulated in ATF6 tamoxifen-induced activation
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between ATF6 tamoxifen-induced activation cells and control cells in the heart left ventricle cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bxdi
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:1473
Cell Typeheart left ventricle
Gene Symbol (human)ATF6
Gene Symbol (mouse)Atf6
Organismmouse
Perturbation Typetamoxifen-induced activation
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM206351, GSM206352, GSM206353
Perturbed SamplesGSM205922, GSM205923, GSM206335
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8322
Gene Expression Omnibus
Transgenic model of selective ATF6 activation: heart
7
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