Enrichment analysis of genes upregulated in PARP2 KO
Canned Analysis
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General Information
AccessionDCA00064448
TitleEnrichment analysis of genes upregulated in PARP2 KO
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between PARP2 KO cells and control cells in the sorted Ter119+CD71+ bone marrow cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bxd3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1474
Cell Typesorted Ter119+CD71+ bone marrow cells
Gene Symbol (human)PARP2
Gene Symbol (mouse)Parp2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM1325331, GSM1325332
Perturbed SamplesGSM1325333, GSM1325334
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE54864
Gene Expression Omnibus
Parp-2 is required for efficient erythropoiesis in mice by limiting replicative stress in erythroid progenitors
7
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