Enrichment analysis of genes downregulated in REST Drug inhibition (X5050)
Canned Analysis
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General Information
AccessionDCA00064809
TitleEnrichment analysis of genes downregulated in REST Drug inhibition (X5050)
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between REST Drug inhibition (X5050) cells and control cells in the NSCs cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bx2c
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1710
Cell TypeNSCs
Gene Symbol (human)REST
Gene Symbol (mouse)Rest
Organismhuman
Perturbation TypeDrug inhibition (X5050)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM999257, GSM999258, GSM999259
Perturbed SamplesGSM999260, GSM999261, GSM999262
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40695
Gene Expression Omnibus
Expression data from NSCs treated with REST inhibitor X5050
7
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