Enrichment analysis of genes upregulated in BMPR2 dominant negative mutation BMPR2delx4+
Canned Analysis
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General Information
AccessionDCA00064844
TitleEnrichment analysis of genes upregulated in BMPR2 dominant negative mutation BMPR2delx4+
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between BMPR2 dominant negative mutation BMPR2delx4+ cells and control cells in the lung cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1by5z
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorHollyWoodland
CREEDS IDgene:1727
Cell Typelung
Gene Symbol (human)BMPR2
Gene Symbol (mouse)Bmpr2
Organismmouse
Perturbation Typedominant negative mutation BMPR2delx4+
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM118653, GSM118658
Perturbed SamplesGSM119286, GSM119287
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE5255
Gene Expression Omnibus
Bone morphogenic protein receptor 2 inactivation in smooth muscle effect on the lung: time course
7
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