Enrichment analysis of genes downregulated in HDAC1 Drug inhibition (0.5mM VPA for 16 hs)
Canned Analysis
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General Information
AccessionDCA00065009
TitleEnrichment analysis of genes downregulated in HDAC1 Drug inhibition (0.5mM VPA for 16 hs)
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between HDAC1 Drug inhibition (0.5mM VPA for 16 hs) cells and control cells in the ES cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bxni
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorFabioAmaral
CREEDS IDgene:1804
Cell TypeES cells
Gene Symbol (human)HDAC1
Gene Symbol (mouse)Hdac1
Organismmouse
Perturbation TypeDrug inhibition (0.5mM VPA for 16 hs)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM590259, GSM590260
Perturbed SamplesGSM590261, GSM590262
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE23956
Gene Expression Omnibus
Gene expression profiles of E14 ESCs treated with low levels of HDAC inhibitors for 16 hrs
7
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