Enrichment analysis of genes downregulated in MYC knock-in
Canned Analysis
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General Information
AccessionDCA00065107
TitleEnrichment analysis of genes downregulated in MYC knock-in
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MYC knock-in cells and control cells in the germinal center B-cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c1dj
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:1847
Cell Typegerminal center B-cells
Gene Symbol (human)MYC
Gene Symbol (mouse)Myc
Organismmouse
Perturbation Typeknock-in
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM968811, GSM968813
Perturbed SamplesGSM968810, GSM968812
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE39443
Gene Expression Omnibus
Genome wide analysis of germinal center MYC positive B-cells
7
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