Enrichment analysis of genes downregulated in CDK8 knockdown
Canned Analysis
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General Information
AccessionDCA00065175
TitleEnrichment analysis of genes downregulated in CDK8 knockdown
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CDK8 knockdown cells and control cells in the unknown cell line stimulated with serum cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c0b1
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1896
Cell Typeunknown cell line stimulated with serum
Gene Symbol (human)CDK8
Gene Symbol (mouse)Cdk8
Organismhuman
Perturbation Typeknockdown
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM475978, GSM475979, GSM475982, GSM475983
Perturbed SamplesGSM475980, GSM475981, GSM475984, GSM475985
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE19199
Gene Expression Omnibus
Expression data from serum-starved control and CDK8 depleted cells following serum stimulation
7
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