Enrichment analysis of genes upregulated in JAK2 activemutant
Canned Analysis
FAIR Metrics
0 evaluations
General Information
AccessionDCA00065254
TitleEnrichment analysis of genes upregulated in JAK2 activemutant
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between JAK2 activemutant cells and control cells in the myeloproliferative neoplasm propagating stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c0y0
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:1949
Cell Typemyeloproliferative neoplasm propagating stem cells
Gene Symbol (human)JAK2
Gene Symbol (mouse)Jak2
Organismmouse
Perturbation Typeactivemutant
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM1094492, GSM1094496, GSM1094500, GSM1094504
Perturbed SamplesGSM1094493, GSM1094497, GSM1094501, GSM1094505
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE44961
Gene Expression Omnibus
Depletion of Jak2V617F MPN-propagating stem cells by interferon-alpha in a murine model of polycythemia vera
7
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.