Enrichment analysis of genes downregulated in WEE1 druginhibition
Canned Analysis
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General Information
AccessionDCA00065439
TitleEnrichment analysis of genes downregulated in WEE1 druginhibition
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between WEE1 druginhibition cells and control cells in the PC3 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bzt6
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorAndrew
CREEDS IDgene:2064
Cell TypePC3
Gene Symbol (human)WEE1
Gene Symbol (mouse)Wee1
Organismhuman
Perturbation Typedruginhibition
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM953063, GSM953067, GSM953071
Perturbed SamplesGSM953064, GSM953068, GSM953072
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38972
Gene Expression Omnibus
Wee1 Inhibition sensitizes prostate cancer cells to Hsp90 inhibitor to activate the intrinsic apoptotic pathway
7
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