Enrichment analysis of genes downregulated in GATA6 KO
Canned Analysis
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General Information
AccessionDCA00065607
TitleEnrichment analysis of genes downregulated in GATA6 KO
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between GATA6 KO cells and control cells in the tissue resident peritoneal macrophages cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c0jr
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2225
Cell Typetissue resident peritoneal macrophages
Gene Symbol (human)GATA6
Gene Symbol (mouse)Gata6
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1143766, GSM1143767, GSM1143768
Perturbed SamplesGSM1143763, GSM1143764, GSM1143765
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE47049
Gene Expression Omnibus
Expression data from wild type and Gata6-deficient tissue resident peritoneal macrophages
7
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