Enrichment analysis of genes downregulated in KLF5 KO
Canned Analysis
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General Information
AccessionDCA00065761
TitleEnrichment analysis of genes downregulated in KLF5 KO
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between KLF5 KO cells and control cells in the dorsal prostate, PTEN-null background cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c0l3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorOliFucMuc
CREEDS IDgene:2318
Cell Typedorsal prostate, PTEN-null background
Gene Symbol (human)KLF5
Gene Symbol (mouse)Klf5
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1418653, GSM1418654, GSM1418655, GSM1418656
Perturbed SamplesGSM1418657, GSM1418658, GSM1418659, GSM1418660
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE58719
Gene Expression Omnibus
Expression data from conditional Klf5 knockout Pten-null mouse prostates
7
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