Enrichment analysis of genes downregulated in HTRA2 KO
Canned Analysis
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General Information
AccessionDCA00065837
TitleEnrichment analysis of genes downregulated in HTRA2 KO
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between HTRA2 KO cells and control cells in the cortex cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bxb4
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatornbongio
CREEDS IDgene:2361
Cell Typecortex
Gene Symbol (human)HTRA2
Gene Symbol (mouse)Htra2
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM326524, GSM326525, GSM326526
Perturbed SamplesGSM326527, GSM326528, GSM326529
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE13033
Gene Expression Omnibus
Differentially expressed genes in brain tissue from HtrA2 knockout mice
7
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