Enrichment analysis of genes upregulated in CYP27B1 KO
Canned Analysis
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General Information
AccessionDCA00065908
TitleEnrichment analysis of genes upregulated in CYP27B1 KO
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between CYP27B1 KO cells and control cells in the genotype/variation: Cyp27b1 flox/flox;Cre+ OR Cre- tissue: breast tumor genetic background: FVB cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1byb3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorgszeto
CREEDS IDgene:2404
Cell Typegenotype/variation: Cyp27b1 flox/flox;Cre+ OR Cre- tissue: breast tumor genetic background: FVB
Gene Symbol (human)CYP27B1
Gene Symbol (mouse)Cyp27b1
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM992462, GSM992463, GSM992464
Perturbed SamplesGSM992465, GSM992466, GSM992467
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40375
Gene Expression Omnibus
Lack of local vitamin D synthesis accelerates breast cancer development after Cyp27B1 gene ablation in mammary epithelium
7
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