Enrichment analysis of genes downregulated in IRF1 OE
Canned Analysis
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General Information
AccessionDCA00066089
TitleEnrichment analysis of genes downregulated in IRF1 OE
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between IRF1 OE cells and control cells in the Huh-7 human hepatoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1byqi
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:2502
Cell TypeHuh-7 human hepatoma cells
Gene Symbol (human)IRF1
Gene Symbol (mouse)Irf1
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM659573, GSM659574, GSM659575
Perturbed SamplesGSM659576, GSM659577, GSM659578
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE26817
Gene Expression Omnibus
Impact of IRF1 on transcriptome changes in Huh-7 human hepatoma cells and STAT1-deficient human fibroblasts
7
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