Enrichment analysis of genes downregulated in CYFIP1 OE
Canned Analysis
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General Information
AccessionDCA00066365
TitleEnrichment analysis of genes downregulated in CYFIP1 OE
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CYFIP1 OE cells and control cells in the SY5Y cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c06j
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormauroccm
CREEDS IDgene:2690
Cell TypeSY5Y
Gene Symbol (human)CYFIP1
Gene Symbol (mouse)Cyfip1
Organismmouse
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1003284, GSM1003286, GSM1003287
Perturbed SamplesGSM1003283, GSM1003285, GSM1003288
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40852
Gene Expression Omnibus
Overexpression of disease-associated CYFIP1 alters cellular and synaptic morphology through mTOR dysregulation of mTOR signaling
7
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