Enrichment analysis of genes downregulated in MS4A1 blockade of gene product (CD20)
Canned Analysis
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General Information
AccessionDCA00066367
TitleEnrichment analysis of genes downregulated in MS4A1 blockade of gene product (CD20)
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between MS4A1 blockade of gene product (CD20) cells and control cells in the Rheumatoid arthritic synovium cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bz0m
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorVICENTE
CREEDS IDgene:2692
Cell TypeRheumatoid arthritic synovium
Gene Symbol (human)MS4A1
Gene Symbol (mouse)Ms4a1
Organismhuman
Perturbation Typeblockade of gene product (CD20)
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM607508, GSM609031, GSM609033, GSM609035, GSM609037, GSM609386, GSM609388, GSM609390, GSM609392, GSM609394, GSM609396, GSM609398
Perturbed SamplesGSM607509, GSM609032, GSM609034, GSM609036, GSM609038, GSM609387, GSM609389, GSM609391, GSM609393, GSM609395, GSM609397, GSM609399
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE24742
Gene Expression Omnibus
Rheumatoid arthritic synovium response to rituximab
12
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