Enrichment analysis of genes upregulated in MTDH KD
Canned Analysis
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General Information
AccessionDCA00066808
TitleEnrichment analysis of genes upregulated in MTDH KD
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between MTDH KD cells and control cells in the MCF-7 breast cancer cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1byqs
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:2954
Cell TypeMCF-7 breast cancer cells
Gene Symbol (human)MTDH
Gene Symbol (mouse)Mtdh
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM1425177, GSM1425178, GSM1425179
Perturbed SamplesGSM1425180, GSM1425181, GSM1425182
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE59055
Gene Expression Omnibus
A newly identified spliced isoform of metadherin differently regulates the global transcriptomic profile in MCF-7 breast cancer cells
7
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