Enrichment analysis of genes downregulated in PIK3CA KD
Canned Analysis
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General Information
AccessionDCA00066937
TitleEnrichment analysis of genes downregulated in PIK3CA KD
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between PIK3CA KD cells and control cells in the H69 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bzk3
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorApozar
CREEDS IDgene:3033
Cell TypeH69
Gene Symbol (human)PIK3CA
Gene Symbol (mouse)Pik3ca
Organismhuman
Perturbation TypeKD
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM996643, GSM996644, GSM996645
Perturbed SamplesGSM996649, GSM996650, GSM996651
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE40564
Gene Expression Omnibus
Targeting the Phosphoinositide 3-Kinase p110 Isoform Impairs Cell Proliferation, Survival and Tumor Growth in Small Cell Lung Cancer
7
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