Enrichment analysis of genes upregulated in ADAM17 Conditional KO in keratinocytes
Canned Analysis
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General Information
AccessionDCA00067046
TitleEnrichment analysis of genes upregulated in ADAM17 Conditional KO in keratinocytes
DescriptionAn enrichment analysis was performed on the top 500 most upregulated genes identified by applying the Characteristic Direction method comparing gene expression between ADAM17 Conditional KO in keratinocytes cells and control cells in the Keratinocytes cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1byuk
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis CuratorCarolet
CREEDS IDgene:3100
Cell TypeKeratinocytes
Gene Symbol (human)ADAM17
Gene Symbol (mouse)Adam17
Organismmouse
Perturbation TypeConditional KO in keratinocytes
Characteristic Direction parameters
Gene Setupregulated
Gene Set Size500
Control SamplesGSM950400, GSM950402
Perturbed SamplesGSM950401, GSM950403
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE38830
Gene Expression Omnibus
Conditional keratinocyte-specific ADAM17 knockout in mice alters skin homeostasis
7
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