Enrichment analysis of genes downregulated in PRDM14 KO
Canned Analysis
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General Information
AccessionDCA00067055
TitleEnrichment analysis of genes downregulated in PRDM14 KO
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between PRDM14 KO cells and control cells in the mESC mouse embryonic stem cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bzhu
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormaroulisv
CREEDS IDgene:3106
Cell TypemESC mouse embryonic stem cells
Gene Symbol (human)PRDM14
Gene Symbol (mouse)Prdm14
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1105757, GSM1105758, GSM1105759
Perturbed SamplesGSM1105754, GSM1105755, GSM1105756
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE45507
Gene Expression Omnibus
Genome-wide identification of genes differentially expressed between wild-type and Prdm14-deficient ES cells grown in 2i culture conditions.
7
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