Enrichment analysis of genes downregulated in ZMPSTE24 Deficiency
Canned Analysis
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General Information
AccessionDCA00067357
TitleEnrichment analysis of genes downregulated in ZMPSTE24 Deficiency
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between ZMPSTE24 Deficiency cells and control cells in the Embryonic fibroblasts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bxkh
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:533
Cell TypeEmbryonic fibroblasts
Gene Symbol (human)ZMPSTE24
Gene Symbol (mouse)Zmpste24
Organismmouse
Perturbation TypeDeficiency
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM621319, GSM621320, GSM621321
Perturbed SamplesGSM621322, GSM621323, GSM621324
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE25257
Gene Expression Omnibus
Zinc metalloproteinase Zmpste24 deficiency effect on embryonic fibroblasts in vitro
7
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