Enrichment analysis of genes downregulated in PPARA KO
Canned Analysis
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General Information
AccessionDCA00067371
TitleEnrichment analysis of genes downregulated in PPARA KO
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between PPARA KO cells and control cells in the Livers cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bxwb
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:543
Cell TypeLivers
Gene Symbol (human)PPARA
Gene Symbol (mouse)Ppara
Organismmouse
Perturbation TypeKO
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM461976, GSM461977, GSM461978, GSM461979
Perturbed SamplesGSM461984, GSM461985, GSM461986, GSM461987
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE18564
Gene Expression Omnibus
Peroxisome proliferator-activated receptor alpha deficiency effect on phthalate-exposed liver
7
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