Enrichment analysis of genes downregulated in CTNNB1 Inactivation
Canned Analysis
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General Information
AccessionDCA00067519
TitleEnrichment analysis of genes downregulated in CTNNB1 Inactivation
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CTNNB1 Inactivation cells and control cells in the Intestinal crypts cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1c1k7
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:655
Cell TypeIntestinal crypts
Gene Symbol (human)CTNNB1
Organismmouse
Perturbation Type Inactivation
None{u'vals': [0.0500271351399, 0.0470078683888, 0.0463499929723, 0.0421347298706, 0.0410327840723, 0.0404728999582, 0.037450802955, 0.0366356547004, -0.0361597994871, 0.0355114987508, 0.035488414554, 0.0347484857954, 0.0336043791938, -0.0334287414501, 0.0333
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM219114, GSM219115
Perturbed SamplesGSM219116, GSM219117
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE8818
Gene Expression Omnibus
Beta-catenin inactivation effect on intestinal crypts
7
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