Enrichment analysis of genes downregulated in CREB1 DEPLETION
Canned Analysis
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General Information
AccessionDCA00067567
TitleEnrichment analysis of genes downregulated in CREB1 DEPLETION
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between CREB1 DEPLETION cells and control cells in the K562 myeloid leukemia cell line cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bwhx
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatorcadimo
CREEDS IDgene:68
Cell TypeK562 myeloid leukemia cell line
Gene Symbol (human)CREB1
Gene Symbol (mouse)Creb1
Organismhuman
Perturbation TypeDEPLETION
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM304303, GSM304304, GSM304479, GSM304480, GSM304481, GSM304482, GSM304483, GSM304484, GSM304486, GSM304498
Perturbed SamplesGSM304487, GSM304488, GSM304489, GSM304490, GSM304491, GSM304492, GSM304493, GSM304494, GSM304495, GSM304496
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE12056
Gene Expression Omnibus
Transcription factor CREB depletion effect on myeloid leukemic cell line
7
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