Enrichment analysis of genes downregulated in RRP1B OE
Canned Analysis
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General Information
AccessionDCA00067703
TitleEnrichment analysis of genes downregulated in RRP1B OE
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between RRP1B OE cells and control cells in the cell line MDA-MB-231 cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bydw
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormtahay
CREEDS IDgene:821
Cell Typecell line MDA-MB-231
Gene Symbol (human)RRP1B
Gene Symbol (mouse)Rrp1b
Organismhuman
Perturbation TypeOE
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1304753, GSM1304754, GSM1304755, GSM1304756, GSM1304757
Perturbed SamplesGSM1304748, GSM1304749, GSM1304750, GSM1304751, GSM1304752
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE53979
Gene Expression Omnibus
Expression data from MDA-MB-231 cells over-expressing RRP1B and MDA-MB-231 control cells with endogenous RRP1B levels
7
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