Enrichment analysis of genes downregulated in NOTCH1 INHIBITION
Canned Analysis
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General Information
AccessionDCA00067761
TitleEnrichment analysis of genes downregulated in NOTCH1 INHIBITION
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between NOTCH1 INHIBITION cells and control cells in the MOLT4 (T-cell acute lymphoblast leukemia) cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bza2
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
CREEDS IDgene:88
Cell TypeMOLT4 (T-cell acute lymphoblast leukemia) cells
Gene Symbol (human)NOTCH1
Gene Symbol (mouse)Notch1
Organismhuman
Perturbation TypeINHIBITION
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM149395, GSM149396, GSM149397
Perturbed SamplesGSM149398, GSM149399, GSM149400
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE6495
Gene Expression Omnibus
T-cell acute lymphoblastic leukemia cell line response to Notch receptor inhibition
7
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