Enrichment analysis of genes downregulated in BRAF Drug inhibition
Canned Analysis
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General Information
AccessionDCA00067767
TitleEnrichment analysis of genes downregulated in BRAF Drug inhibition
DescriptionAn enrichment analysis was performed on the top 500 most downregulated genes identified by applying the Characteristic Direction method comparing gene expression between BRAF Drug inhibition cells and control cells in the A375 melanoma cells cell type.
Analysis URLhttp://amp.pharm.mssm.edu/Enrichr/enrich?dataset=1bwul
Upload DateSeptember 20, 2017
Uploadermaayanlab
Metadata
Analysis Curatormauroccm
CREEDS IDgene:883
Cell TypeA375 melanoma cells
Gene Symbol (human)BRAF
Gene Symbol (mouse)Braf
Organismhuman
Perturbation TypeDrug inhibition
Characteristic Direction parameters
Gene Setdownregulated
Gene Set Size500
Control SamplesGSM1052615, GSM1052616, GSM1052617
Perturbed SamplesGSM1052618, GSM1052619, GSM1052620
Tools used in the analysis
Keyword
Dataset Accession
Enrichr
Published May 2016
A comprehensive gene set enrichment analysis web server 2016 update
7759
65
Characteristic Direction
Published March 2014
A geometrical multivariate approach to identify differentially expressed genes
26829
Datasets used in the analysis
Keyword
Tool Name
GSE42872
Gene Expression Omnibus
Oncogenic BRAF harboring melanoma cell line response to BRAF inhibition
12
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