Analysis of Pro-Inflammatory Gene Activation and RNA Processing by RNAseq of Nascent Transcripts [supplement]
Transcriptomics Dataset
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General Information
AccessionGSE38892
TitleAnalysis of Pro-Inflammatory Gene Activation and RNA Processing by RNAseq of Nascent Transcripts [supplement]
DescriptionNote: These datasets are in supplement to, but separate from, Geo GSE32916. We examined pro-inflammatory gene activation in activated wildtype and IFNAR-/- murine macrophages by performing RNA-Seq with poly(A) enriched transcripts. This experimental strategy allowed a global, high-resolution analysis of the transcriptional regulation of diverse classes of co-expressed genes and allowed us to identify co-expressed gene classes that may depend on IFN-signaling for its expression. The results provide quantitative insights into the relationship between transcription and distinct promoter and chromatin properties.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE38892
RepositoryGene Expression Omnibus
Tools used to analyze the dataset
Dataset Accession
ARCHS4
Published September 2017
ARCHS4 provides access to gene counts from HiSeq 2000 and HiSeq 2500 platforms for human and mouse experiments from GEO ...
4645
Clustergrammer
Published October 2017
Web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable heatmaps
4645
Canned Analyses generated with the dataset
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Tool Name
Interactive heatmap visualization of RNA-seq dataset GSE38892
ARCHS4, Clustergrammer
Highly interactive web-based heatmap visualization of the top 500 most variable genes in t...
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