RNA-seq Generated Transcriptional Profile of H2O2 Treated HCT116 vs. Untreated HCT116
Transcriptomics Dataset
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General Information
AccessionGSE75962
TitleRNA-seq Generated Transcriptional Profile of H2O2 Treated HCT116 vs. Untreated HCT116
DescriptionOxidative stress, is considered to be a key risk state for a variety of human diseases, which can upregulate transcriptional expression of DNA repair genes. However, it remains elusive whether all or just a portion of DNA repair genes can be upregulated in response to oxidative stress. Therefore, the changes in expression pattern of DNA repair genes and how they are regulated in response to oxidative stress need to be elucidated. In this study, we performed RNA-seq to generate expression profile and identified subsets of induced and repressed DNA repair genes in colorectal cancer cell line exposure to hydrogen peroxide.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE75962
RepositoryGene Expression Omnibus
Tools used to analyze the dataset
Dataset Accession
Clustergrammer
Published October 2017
Web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable heatmaps
4645
ARCHS4
Published September 2017
ARCHS4 provides access to gene counts from HiSeq 2000 and HiSeq 2500 platforms for human and mouse experiments from GEO ...
4645
Canned Analyses generated with the dataset
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Tool Name
Interactive heatmap visualization of RNA-seq dataset GSE75962
ARCHS4, Clustergrammer
Highly interactive web-based heatmap visualization of the top 500 most variable genes in t...
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