Small RNA and mRNA transcriptome profiling in wildtype mice at multiple stages of spermatogenesis, from whole testis at day 1 postpartum (pp), day 3 pp, and day 7 pp and purified leptotene/zygotene and pachytene spermatocytes.
Transcriptomics Dataset
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General Information
AccessionGSE83264
TitleSmall RNA and mRNA transcriptome profiling in wildtype mice at multiple stages of spermatogenesis, from whole testis at day 1 postpartum (pp), day 3 pp, and day 7 pp and purified leptotene/zygotene and pachytene spermatocytes.
DescriptionMicroRNAs are essential for spermatogenesis. However, the stagespecific requirements for specific miRNAs in the male mammalian germ line remain largely uncharacterized. The miR34 family is, to date, the only miRNA proven to be necessary for the production of sperm in mice, though its germline roles are poorly understood. Here, we generate and analyze paired small RNA and mRNA profiles across different stages of germline development in male mice, focusing on time points shortly before and during meiotic prophase I.
Landing Pagehttps://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE83264
RepositoryGene Expression Omnibus
Tools used to analyze the dataset

Dataset Accession

ARCHS4
Published September 2017
ARCHS4 provides access to gene counts from HiSeq 2000 and HiSeq 2500 platforms for human and mouse experiments from GEO ...
4645
Clustergrammer
Published October 2017
Web-based tool for visualizing and analyzing high-dimensional data as interactive and shareable heatmaps
4645
Canned Analyses generated with the dataset

Dataset Accession
Tool Name

Interactive heatmap visualization of RNA-seq dataset GSE83264
Highly interactive web-based heatmap visualization of the top 500 most variable genes in t...
Interactive heatmap visualization of RNA-seq dataset GSE83264
Highly interactive web-based heatmap visualization of the top 500 most variable genes in t...
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