General Information
| Description | C++ libraries for pairwise local alignment E-values |
| Homepage | http://go.usa.gov/3GTSW |
Publications
ALP & FALP: C++ libraries for pairwise local alignment E-values
Motivation:
Pairwise local alignment is an indispensable tool for molecular biologists. In real time (i.e. in about 1 s), ALP (Ascending Ladder Program) calculates the E-values for protein–protein or DNA–DNA local alignments of random sequences, for arbitrary substitution score matrix, gap costs and letter abundances; and FALP (Frameshift Ascending Ladder Program) performs a similar task, although more slowly, for frameshifting DNA-protein alignments.
Availability and implementation:
To permit other C++ programmers to implement the computational efficiencies in ALP and FALP directly within their own programs, C++ source codes are available in the public domain at http://go.usa.gov/3GTSW under ‘ALP’ and ‘FALP’, along with the standalone programs ALP and FALP.
Contact:
spouge@nih.gov
Supplementary information:
Supplementary data are available at Bioinformatics online.
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