General Information
| Description | A web server for ancestral sequence reconstruction |
| Homepage | http://ancestors.bioinfo.uqam.ca/ancestorWeb/ |
Publications
Ancestors 1.0: a web server for ancestral sequence reconstruction
Summary:
The computational inference of ancestral genomes consists of five difficult steps: identifying syntenic regions, inferring ancestral arrangement of syntenic regions, aligning multiple sequences, reconstructing the insertion and deletion history and finally inferring substitutions. Each of these steps have received lot of attention in the past years. However, there currently exists no framework that integrates all of the different steps in an easy workflow. Here, we introduce Ancestors 1.0, a web server allowing one to easily and quickly perform the last three steps of the ancestral genome reconstruction procedure. It implements several alignment algorithms, an indel maximum likelihood solver and a context-dependent maximum likelihood substitution inference algorithm. The results presented by the server include the posterior probabilities for the last two steps of the ancestral genome reconstruction and the expected error rate of each ancestral base prediction.
Availability:
The Ancestors 1.0 is available at http://ancestors.bioinfo.uqam.ca/ancestorWeb/.
Contact:
diallo.abdoulaye@uqam.ca
Related Tools
MEGA-CC
Published August 2012
Computing core of molecular evolutionary genetics analysis program for automated and iterative data analysis
A counting renaissance
Published October 2012
Combining stochastic mapping and empirical Bayes to quickly detect amino acid sites under positive selection
RidgeRace
Published August 2014
Ridge regression for continuous ancestral character estimation on phylogenetic trees
Historian
Published January 2017
Accurate reconstruction of ancestral sequences and evolutionary rates
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
