General Information
| Description | A knowledge database for tissue-enriched genes |
| Homepage | http://C-It.mpi-bn.mpg.de |
Publications
C-It: a knowledge database for tissue-enriched genes
Motivation:
Due to the development of high-throughput technologies such as microarrays, it has become possible to determine genome-wide expression changes in a single experiment. Although much attention has been paid to identify differentially expressed genes, the functions of tens of thousands of genes in different species still remain unknown.
Results:
C-It is a knowledge database that has its focus on ‘uncharacterized genes’. C-It contains expression profiles of various tissues from human, mouse, rat, chicken and zebrafish. By applying our previously introduced algorithm DGSA (Database-Dependent Gene Selection and Analysis), it is possible to screen for uncharacterized, tissue-enriched genes in the species mentioned above. C-It is designed to include further expression studies, which might provide more comprehensive coverage of gene expression patterns and tissue-enriched splicing isoforms. We propose that C-It will be an excellent starting point to study uncharacterized genes.
Availability:
C-It is freely available online without registration at http://C-It.mpi-bn.mpg.de
Contact:
thomas.braun@mpi-bn.mpg.de; shizuka.uchida@mpi-bn.mpg.de
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